How Do Toxins Affect the Parasympathetic Nervous System?
Toxins can disrupt the normal functioning of the parasympathetic nervous system through various mechanisms. Certain organophosphates and carbamates, commonly found in pesticides, inhibit acetylcholinesterase, leading to an accumulation of acetylcholine. This excess acetylcholine overstimulates the parasympathetic nervous system, causing symptoms such as excessive salivation, lacrimation, urination, diarrhea, gastrointestinal distress, and emesis, collectively known as the SLUDGE syndrome.
