How Does Aging Affect Toxicological Responses in Adults?
In adults, aging can lead to changes in organ function and body composition, influencing toxicological responses. For example, decreased liver function can slow down the metabolism of toxins, leading to prolonged exposure and potential toxicity. The reduction in renal function observed with aging can impair the excretion of toxins, increasing systemic exposure. Additionally, age-related changes in the cardiovascular system can alter the distribution of substances within the body.