How does ALT relate to other liver enzymes in toxicology?
In toxicology, ALT is often assessed alongside other liver enzymes such as aspartate transaminase (AST), alkaline phosphatase (ALP), and gamma-glutamyl transferase (GGT). The ratio of AST to ALT can provide additional insights into the type of liver injury. For instance, a higher AST/ALT ratio is often associated with alcohol-related liver damage, whereas a lower ratio might indicate non-alcoholic causes. Elevated ALP and GGT levels are more indicative of cholestatic liver injury.