CYP3A5's role in metabolizing toxic compounds can also influence toxicity outcomes. Some toxins require metabolic activation by CYP3A5 to become harmful, while others are detoxified through its action. Variations in enzyme activity can thus determine an individual's susceptibility to certain toxicants. Toxicologists must consider CYP3A5's contribution when evaluating risk assessments and exposure limits for environmental and occupational toxins.
