How Does CYP450 Contribute to Drug-Drug Interactions?
Drug-drug interactions often involve CYP450 enzymes. When two drugs are metabolized by the same enzyme, they can compete for binding, leading to altered levels of one or both drugs. For instance, if one drug is a potent CYP450 inhibitor, it can decrease the metabolism of another drug, potentially leading to toxicity. Conversely, a drug that induces CYP450 enzymes can increase the metabolism of another drug, reducing its efficacy.
