How Does FISH Compare to Other Techniques in Toxicology?
FISH is often compared with other genetic analysis techniques such as PCR and next-generation sequencing (NGS). While PCR is excellent for amplifying and detecting specific DNA fragments, it lacks the ability to visualize chromosomal location. NGS provides comprehensive genomic data but can be more expensive and complex. FISH offers a unique advantage in its ability to provide spatial visualization of genetic changes, which is particularly useful for identifying chromosomal rearrangements and aneuploidy in a cellular context.
