How Does IgA Deficiency Affect Toxicological Responses?
Individuals with IgA deficiency may be more vulnerable to the adverse effects of environmental and chemical toxins due to compromised mucosal barriers. The lack of IgA can result in increased permeability of mucous membranes, allowing toxins to enter the bloodstream more easily. This situation can exacerbate toxicological effects and alter the pharmacokinetics of certain drugs.