In regulatory toxicology, sharing information is critical for the development of guidelines and standards that protect public health and the environment. By accessing a wider pool of data, regulatory agencies can perform more robust safety evaluations of chemicals and products. Collaborative efforts between agencies, such as the European Chemicals Agency (ECHA) and the United States Environmental Protection Agency (EPA), enable harmonization of regulations and facilitate the implementation of best practices globally. This collaborative approach also encourages the adoption of alternative testing methods, reducing the reliance on animal testing.