Tetanospasmin is one of the most potent toxins known. It targets the nervous system, specifically the motor neurons. Once the toxin enters the body through wounds, it travels along the peripheral nerves to the central nervous system. Tetanospasmin blocks the release of neurotransmitters like glycine and gamma-aminobutyric acid (GABA), which are crucial for muscle relaxation. This blockade leads to the characteristic muscle spasms and rigidity seen in tetanus.
