barrier function

How does the skin act as a barrier?

The skin is the body's largest organ and serves as the first line of defense against environmental toxins. Its outermost layer, known as the stratum corneum, is rich in lipids and keratin, which help to repel water and fat-soluble substances. The intact skin is highly effective at preventing the penetration of many toxic agents. However, factors like cuts, abrasions, or certain chemicals can compromise this barrier, increasing the risk of exposure.

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