How is ADME Information Applied in Risk Assessment?
ADME data are critical in toxicological risk assessment as they help determine the potential exposure levels and the dose-response relationship of toxicants. Understanding ADME allows for the identification of vulnerable populations and the establishment of safety thresholds and guidelines. It also aids in the development of antidotes and treatment strategies for managing exposure to harmful substances.
In conclusion, ADME processes are integral to toxicology as they influence the toxicokinetics and overall toxicity of chemicals. A comprehensive understanding of these processes is essential for accurate risk assessment, exposure management, and the development of therapeutic interventions.
