Excretion is the process by which the body eliminates the toxicant and its metabolites. The primary routes of excretion include the kidneys (urine), liver (bile), lungs (exhaled air), and skin (sweat). Efficient excretion reduces the duration of exposure and the overall toxic burden. However, some toxicants may be reabsorbed or may not be excreted efficiently, leading to prolonged or cumulative toxicity.