How is Pyruvate Dehydrogenase Deficiency Related to Toxicology?
In toxicology, PDD is relevant because it can alter the way individuals metabolize certain chemicals and drugs. Individuals with PDD may have an increased sensitivity to compounds that impair mitochondrial function or those that require proper energy metabolism for detoxification. This sensitivity can lead to an accumulation of toxic metabolites, exacerbating the effects of exposure to certain toxins.
