For sunscreen to be effective, it must be applied correctly. This means using an adequate amountâabout one ounce (a shot glass full) to cover all exposed skinâand applying it 15-30 minutes before sun exposure. Reapplication is key, especially after swimming, sweating, or towel drying, at least every two hours. It is also advisable to use a broad-spectrum sunscreen that protects against both UVA and UVB rays. By following these guidelines, individuals can maximize their protection against UV-related toxicity.