Some of the most common toxicants that affect the pancreas include:
Alcohol: Chronic alcohol consumption is a well-known risk factor for pancreatitis. Alcohol can cause oxidative stress and damage pancreatic cells. Medications: Drugs such as corticosteroids, thiazide diuretics, and some antibiotics have been linked to drug-induced pancreatitis. Heavy metals: Metals like lead, cadmium, and arsenic can accumulate in the pancreas, potentially leading to diabetes and other endocrine disorders. Environmental pollutants: Exposure to polychlorinated biphenyls (PCBs) and dioxins can disrupt endocrine function and promote carcinogenesis in the pancreas.