death receptors

What are Death Receptors?

Death receptors are a subset of the tumor necrosis factor receptor (TNFR) superfamily, which are characterized by a cytoplasmic death domain that transduces apoptotic signals. These receptors, including Fas (CD95), TRAIL receptors, and TNFR1, are activated by their respective ligands, leading to the induction of programmed cell death or apoptosis.

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