What are Epigenome Wide Association Studies (EWAS)?
Epigenome Wide Association Studies, commonly referred to as EWAS, are research approaches that aim to identify epigenetic changes across the entire genome that are associated with exposure to environmental factors, including toxicants. Unlike genetic association studies that look at variations in DNA sequence, EWAS focus on epigenetic modifications such as DNA methylation, histone modifications, and non-coding RNA expression. These modifications can influence gene expression without altering the underlying DNA sequence.