Genomics is the study of an organism's entire genetic makeup, or genome. It involves the analysis of DNA sequences, which can reveal susceptibilities to certain diseases or responses to environmental factors, including toxic substances. Epigenomics, on the other hand, refers to the study of chemical modifications on the DNA and histone proteins that do not change the DNA sequence but can influence gene expression. These modifications can be affected by environmental factors, including exposure to toxins, and can be heritable.