What are the Risks Associated with COX-2 Inhibitors?
While COX-2 inhibitors reduce gastrointestinal side effects, they have been linked to increased cardiovascular risks. Studies have indicated that some COX-2 inhibitors, like rofecoxib (Vioxx), may increase the risk of heart attack and stroke. This has led to a re-evaluation of their safety profile and the withdrawal of some drugs from the market.