Warfarin and antibiotics: Certain antibiotics can increase the effects of warfarin, a blood thinner, raising the risk of bleeding. Antidepressants and MAO inhibitors: Combining these can lead to severe hypertension due to excessive monoamine oxidase inhibition. Statins and grapefruit juice: Grapefruit juice can inhibit the CYP3A4 enzyme, increasing statin levels and the risk of muscle damage.
