What Are Some Examples of Polymorphisms Relevant to Toxicology?
There are numerous polymorphisms relevant to toxicology. A well-known example is the N-acetyltransferase polymorphism, which can affect the metabolism of certain drugs and carcinogens. Another is the polymorphism in the MDR1 gene, which encodes for P-glycoprotein, a transporter protein that affects drug distribution and excretion.