Hepatocellular injury can be caused by a variety of factors, including:
Toxicants: Chemicals and environmental pollutants can directly damage liver cells. Drugs: Certain medications, such as acetaminophen, antibiotics, and anti-seizure drugs, are known to cause liver injury. Alcohol: Chronic alcohol consumption leads to the accumulation of toxic metabolites, resulting in liver damage. Viral Infections: Hepatitis viruses (A, B, C, D, and E) are significant causes of liver damage. Autoimmune diseases: Conditions like autoimmune hepatitis can lead to immune-mediated liver injury.