What Are Some Examples of Species-Specific Toxicity?
Historical cases highlight the importance of considering species-specific differences:
Thalidomide: This drug caused severe birth defects in humans but did not show the same teratogenic effects in some animal models initially used for testing. Paracetamol (Acetaminophen): While safe for humans at therapeutic doses, cats lack the enzyme necessary to metabolize this drug safely, leading to toxicity.
