Several CYP enzymes are particularly important in drug metabolism. CYP3A4 is one of the most abundant CYP enzymes in the liver and is responsible for metabolizing approximately 50% of all drugs. CYP2D6 is another crucial enzyme, involved in the metabolism of many pharmaceuticals, including antidepressants and opioids. Other notable CYP enzymes include CYP1A2, CYP2C9, and CYP2C19, each with their own specific substrates and roles in drug metabolism.
