How Can CYP Enzymes Lead to Drug-Drug Interactions?
Drug-drug interactions often occur due to the involvement of CYP enzymes. When two drugs are metabolized by the same CYP enzyme, they can compete for the enzyme, leading to altered levels of one or both drugs. Inhibitors of CYP enzymes can increase the concentration of drugs metabolized by those enzymes, potentially leading to toxicity. Conversely, inducers of CYP enzymes can decrease drug levels, reducing efficacy. Understanding these interactions is crucial for predicting and managing potential adverse effects.
