One of the primary advantages of the BCOP assay is its ability to significantly reduce the need for in vivo testing, aligning with the 3Rs principles (Replacement, Reduction, and Refinement) in animal research. Additionally, the BCOP assay is cost-effective and provides results within a short timeframe. It has been validated and accepted by various regulatory agencies, including the OECD (Organisation for Economic Co-operation and Development), making it a reliable choice for industries focused on cosmetics, pharmaceuticals, and chemicals.