As HCFCs are being phased out, industries are transitioning to alternative substances that have a lower environmental impact. Some of these alternatives include hydrofluoroolefins (HFOs), which have an ultra-low GWP, and natural refrigerants like ammonia, carbon dioxide, and hydrocarbons. These alternatives offer a more sustainable option for applications previously reliant on HCFCs. The choice of alternative depends on application requirements, safety standards, and regulatory frameworks.