What are the Analytical Methods to Study Sulfation?
Several analytical techniques are employed to study sulfation and its role in toxicology: - Enzyme Assays: Used to measure the activity of sulfotransferases in tissue samples or cell cultures. - Mass Spectrometry: Enables the identification and quantification of sulfated metabolites in biological fluids. - Genotyping: Detects genetic polymorphisms in sulfotransferase genes that may influence enzyme function.