Several challenges can complicate blood toxicology:
- Matrix Effects: Blood contains various components that can interfere with the detection of toxins. - Metabolism: Once in the bloodstream, many toxins are rapidly metabolized, which can complicate detection. - Sample Contamination: Proper collection and storage are crucial to avoid contamination that could skew results. - Interindividual Variability: Differences in age, sex, health status, and genetic makeup can influence how toxins are processed and detected in blood.