What are the challenges in implementing these alternatives?
Despite the many benefits, there are challenges to the widespread adoption of alternative methods. Validation and acceptance by regulatory bodies are significant hurdles. Regulatory agencies often require extensive validation data to ensure that alternative methods are as reliable as traditional animal tests.
Moreover, some complex biological interactions are difficult to replicate outside of a whole organism. For certain types of toxicity, such as systemic effects or chronic exposure, animal models may still provide valuable insights. The development of comprehensive databases and improved computational models is crucial to overcoming these limitations.
