What Factors Can Affect Glutathione Peroxidase Activity?
Several factors can modulate GPx activity, including:
Selenium Levels: GPx is a selenoprotein, and its activity is highly dependent on selenium availability. Genetic Variations: Polymorphisms in GPx genes can affect enzyme efficiency and expression levels. Dietary Factors: Nutrients like vitamins C and E can influence GPx activity by modulating oxidative stress levels. Environmental Exposures: Toxins and pollutants may either induce or inhibit GPx activity depending on the nature and duration of exposure.