Safety assessment faces several challenges, including:
Ethical Considerations: The use of animals in testing raises ethical concerns, prompting the development of alternative methods. Complexity of Mixtures: Real-world exposures often involve mixtures of multiple chemicals, complicating the assessment. Variability in Responses: Differences in genetic makeup, age, sex, and health status can affect how individuals respond to toxins. Data Gaps: Limited data on certain chemicals can hinder accurate risk assessments.