What Are the Key Methods Used in Safety Assessment?
Various methods are employed in safety assessment, including:
Toxicokinetics and toxicodynamics: Studying how a substance is absorbed, distributed, metabolized, and excreted by the body, and its biological effects. In vitro testing: Using cell cultures to evaluate the toxic effects of substances. Animal studies: Conducting experiments on animals to understand potential human health effects. Computational toxicology: Using computer models to predict toxicological outcomes based on chemical structure and biological data. Human volunteer studies: Conducting controlled clinical trials to assess safety in humans, typically for pharmaceuticals.