While biomarkers offer significant advantages, their use also presents challenges. Some of these challenges include:
Specificity and Sensitivity: Finding biomarkers that are both specific to a particular toxicant and sensitive enough to detect low levels of exposure can be difficult. Validation: Biomarkers need rigorous validation to ensure they accurately reflect the exposure or effect of a toxicant. Ethical and Privacy Concerns: The collection and analysis of biological samples raise ethical issues, especially concerning consent and the potential misuse of genetic information.
