What Are the Challenges of Using ESCs in Toxicology?
Despite their potential, there are challenges associated with the use of ESCs in toxicology. One major issue is the ethical concerns surrounding the use of human ESCs, which involve the destruction of embryos. Advances in alternative methods, such as induced pluripotent stem cells (iPSCs), can mitigate ethical concerns. Additionally, standardizing differentiation protocols and ensuring reproducibility across experiments are ongoing challenges.
