Can Acetyl CoA Levels Be Therapeutically Modulated?
Yes, acetyl CoA levels can be modulated therapeutically. Strategies may include the use of metabolic precursors or cofactors that enhance the activity of enzymes involved in its synthesis. For example, supplementation with lipoic acid or Coenzyme Q10 can support mitochondrial function and acetyl CoA production. Additionally, dietary interventions such as a ketogenic diet can increase acetyl CoA levels by promoting fatty acid oxidation.
