In toxicology, several in vivo models are commonly used, each with its own advantages and limitations. Some of the most popular include:
Rodent models: Mice and rats are frequently used due to their genetic similarities to humans, short life cycles, and well-characterized biology. Zebrafish: These small fish offer a transparent embryo, rapid development, and high fecundity, making them useful for developmental and genetic studies. Non-human primates: Used when closer physiological similarities to humans are necessary, although their use is limited due to ethical considerations and high costs.