What are the common toxicological concerns with Rifampin?
The primary toxicological concerns with rifampin include hepatotoxicity, hypersensitivity reactions, and possible effects on the renal system. Hepatotoxicity is particularly significant due to the liver's role in drug metabolism, which can lead to elevated liver enzymes and, in severe cases, liver failure. Hypersensitivity reactions may range from mild skin rashes to severe, life-threatening conditions such as anaphylaxis.