What Are the Effects of Microtubule-Targeting Drugs?
Microtubule-targeting agents are a class of chemotherapy drugs used to treat cancer. Drugs like paclitaxel and vinca alkaloids are effective because they interfere with microtubule dynamics, which are essential for mitosis. By disrupting microtubule function, these drugs effectively halt cell division, leading to cell death. However, these drugs can also have significant toxic side effects, including neuropathy and myelosuppression, due to their effects on normal cells.