What are the Implications of Autoinduction in Toxicology?
In toxicology, autoinduction has several implications:
Altered Drug Levels: Autoinduction can lead to decreased drug concentrations, potentially resulting in subtherapeutic levels and treatment failure. Increased Toxicity Risk: For drugs with narrow therapeutic indices, autoinduction can lead to fluctuations that may increase the risk of toxicity or adverse effects. Drug Interactions: Autoinduction can complicate drug interactions by altering the metabolism of concomitant medications, potentially leading to unexpected side effects or reduced efficacy.
