What Are the Implications of Proteinuria in Toxicology Studies?
The presence of proteinuria in toxicology studies indicates potential kidney damage due to toxic exposure. It serves as an early warning sign of nephrotoxicity, prompting further investigation and intervention. Proteinuria can help identify the dose-response relationship of a toxin, contributing to risk assessment and the establishment of safety thresholds for exposure. Moreover, it aids in understanding the mechanisms of toxicity, guiding the development of protective measures and therapeutic interventions.
