in vitro systems

What Are the Limitations of In Vitro Systems?

Despite their advantages, in vitro systems have limitations. They may not fully replicate the complexity of living organisms, potentially leading to discrepancies between in vitro and in vivo outcomes. The lack of systemic interactions and metabolic processes that occur in whole organisms can affect the extrapolation of results. Thus, while in vitro studies provide valuable insights, it is often necessary to complement them with animal testing or advanced computational models to ensure comprehensive risk evaluation.

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