What Are the Long-term Effects and Monitoring Requirements?
Long-term use of vinblastine can lead to cumulative toxicities, particularly affecting the bone marrow and nervous system. Continuous monitoring of blood counts is essential to manage myelosuppression. Liver function tests should also be conducted regularly to assess hepatic metabolism. Neurological assessments are important to detect early signs of neuropathy. Patients should be informed about the potential for secondary malignancies, although the risk is relatively low.
