hepatocellular carcinoma

What Are the Major Risk Factors in Toxicology?

Several toxicological risk factors contribute to the development of HCC:
Aflatoxins: These are potent carcinogens produced by molds, particularly Aspergillus species, found in improperly stored grains and nuts.
Alcohol: Chronic alcohol consumption leads to liver cirrhosis and increases the risk of HCC.
Hepatitis B and C: Viral infections can lead to chronic liver inflammation and increase susceptibility to carcinogenic substances.
Environmental Pollutants: Exposure to industrial chemicals and pollutants, such as polycyclic aromatic hydrocarbons (PAHs), can damage liver cells.
Obesity and Diabetes: These conditions can lead to non-alcoholic fatty liver disease (NAFLD), a significant risk factor for HCC.

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