What Are the Mechanisms Behind Drug-Induced Tissue Damage?
The mechanisms of drug-induced tissue damage are complex and multifaceted. They can include direct cytotoxic effects, oxidative stress, immune-mediated reactions, and interference with cellular functions. Some drugs generate reactive oxygen species (ROS), leading to oxidative stress and cellular damage. Others may cause an immune response, resulting in inflammation and tissue injury. Additionally, drugs can disrupt cellular processes such as mitochondrial function or enzyme activity, leading to tissue damage.
