What Are the Challenges in Studying the Wnt Pathway in Toxicology?
Studying the Wnt pathway in toxicology presents several challenges. The pathway is highly complex, with numerous components and cross-talk with other signaling pathways. Additionally, the effects of toxicants can be context-dependent, varying with cell type, developmental stage, and exposure duration. Therefore, it requires sophisticated experimental models and techniques to accurately assess the impact of toxicants on this pathway.
