What are the Mechanisms Behind Edema in Toxicology?
The primary mechanisms behind edema in toxicology include increased capillary permeability, impaired lymphatic drainage, and altered hydrostatic or osmotic pressure. Toxins that cause oxidative stress can damage endothelial cells, increasing capillary permeability and allowing fluid to leak into tissues. Some toxins may also interfere with normal lymphatic function, resulting in inadequate removal of interstitial fluid.
