What are the Mechanisms of Toxicity of Cationic Compounds?
The toxicity of cationic compounds primarily arises from their ability to disrupt cellular functions. They can induce oxidative stress by generating reactive oxygen species (ROS), leading to cell injury and apoptosis. Furthermore, they can interfere with ion channels and transporters, disrupting ionic balance and cellular homeostasis. The binding of cationic compounds to DNA can also result in genotoxic effects, potentially leading to mutagenesis and carcinogenesis.
