What are the Mechanisms of Toxin-Induced Vascular Damage?
The mechanisms by which toxins damage blood vessels include inducing oxidative stress, causing inflammation, and disrupting endothelial function. Oxidative stress results from an imbalance between free radicals and antioxidants, leading to cellular damage. Inflammation can cause further vascular injury and contribute to the formation of atherosclerotic plaques. Toxins may also impair the ability of the endothelium to produce nitric oxide, a critical molecule for vascular relaxation and health.