What Are the Molecular Pathways Involved in Fibrosis?
Fibrosis involves complex molecular pathways. The Transforming Growth Factor-beta (TGF-beta) pathway is a key regulator, promoting the transformation of fibroblasts into myofibroblasts, which are responsible for collagen deposition. Other pathways include the Wnt signaling and the Renin-Angiotensin System, both of which play roles in the progression of fibrosis.